Anti-Cornulin antibodies are used for the immunodetection of the protein encoded by the CRNN gene. In humans, the canonical protein has a reported length of 495 amino acid residues and a mass of 53.5 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in the basal skin layer. A member of the S100-fused protein family, it is reported to promote cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. The gene encoding this protein is implicated in Esophageal cancer. Other names for this target antigen include DRC1, PDRC1, 53 kDa putative calcium-binding protein, 53 kDa squamous epithelial-induced stress protein, 58 kDa heat shock protein, and C1orf10. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species. A number of Cornulin antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.