Anti-PKUalpha antibodies enable researchers to detect and measure the PKUalpha antigen in biological samples. This target is a reported synonym of the TLK2 gene, which encodes tousled like kinase 2. This protein is known to function in chromatin organization and DNA damage pathways, among other biological roles. The human version of PKUalpha has a canonical amino acid length of 772 residues and a protein mass of 87.7 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells. Other names for this target antigen include HsHPK, MRD57, and PKU-ALPHA.