Super-Resolution Microscopes

The Biocompare Microscopes and Cell Imaging Systems search tool enables users to compare different instrument specifications, features, and applications to best serve the unique imaging needs of biological researchers. Contemporary microscopes are stand-alone optical devices that enable the necessary magnification needed to visualize processes at the tissue and cellular levels. Thanks to advances in optical technologies, researchers today can enjoy many choices in instruments. Microscopes and imaging systems can be categorized by their general build (such as upright, inverted, or digital systems) or primary function (stereo/zoom, electron, confocal, super-resolution, in vivo imaging, or slide scanning). Another important consideration is the imaging application, as many instrument models can offer multiple capabilities, such as phase contrast, polarization, luminescence, multi-channel fluorescence, darkfield, live cell imaging, 3D imaging, time-lapse, and more. When choosing an imaging instrument, also consider useful features such as automation compatibility, customization options, remote access, and control chambers. Use the filters on the left to simplify your search and click on the products below for more information.

Conventional light microscopes have long been limited in resolution to around 200 nm in width and 500 nm in depth due to the nature of light diffraction. Resolution at much greater magnifications would have required the use of the electron microscopes. However, with recent methodological discoveries in optics such as Stimulated Emission Depletion (STED), Structured Illumination Microscopy (SIM), Stochastic Optical Reconstruction Microscopy (STORM), Photoactivated Localization Microscopy (PALM), Fluorescence Photoactivation Localization Microscopy (FPALM), resolution down to tens of nanometers in width and a few hundred nanometers in depth is now possible with light microscopy. A new class of “Super-Resolution” microscopes is now available, each tailored to suit a wide variety of imaging applications, such as 3D fluorescence imaging, live cell imaging, colocalization, and even in vivo imaging.

Super-Resolution Microscopes

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Nikon Instruments Inc.
CrestOptics DeepSIM Super-Resolution System
  • Type:
    Super-Resolution System
  • Description:
    DeepSIM super-resolution technology is based on multi-spot lattice structured illumination and provides a reliable and ...
  • Applications:
    Multi-spot lattice structured illumination with 100 nm XY resolution, super-resolved data over 50 µm...
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N-SIM E Super-Resolution Microscope
  • Type:
    Super-Resolution
  • Description:
    Utilizing structured illumination microscopy (SIM) technology, the all-new N-SIM E realizes double the spatial ...
  • Applications:
    Cell Signaling
Citations:
(57)
Evident
IXplore SpinSR Spinning Disk Confocal Microscope
  • Type:
    Widefield/ Spinning Disk Confocal/ Super-Resolution/ Cell ...
  • Description:
    The Olympus IXplore SpinSR confocal microscope surpasses the limits of conventional optical microscopes while balancing ...
  • Applications:
    Live Cell Imaging
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Citations:
(13)
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Nikon Instruments Inc.
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Nikon Instruments Inc.
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