Consistent Detection of H3K27M Mutant Histone H3 in Mouse Tissue

Neurosurgery
University of Florida
Research Scientist

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Cell Signaling Technology

Product Name:

Histone H3 (K27M Mutant Specific) (D3B5T) Rabbit Monoclonal Antibody

Catalog Number:

74829

Clone Number:

N/A

Info: Supplier Page 

Browse Similar Products: Rabbit Antibody Products

Tested by Western blot on mouse lung tissue at 1:1000 dilution. The antibody produced a strong, clear signal with low background and good reproducibility. I detected both the H3K27M mutant signal and total Histone H3 in my samples. Overall, a reliable antibody for western blot applications.

Experimental Design and Results Summary

Applications

Western blot

Sample

Lung Mouse Tissue

Primary Incubation

1:1000 overnight 4 C

Blocking Agent

SuperBlock™ T20 (TBS) Blocking Buffer

Secondary Incubation

1:10000 Rabbit 4 hours RT

Tertiary Incubation

N/A

Detection

Chemiluminescent

Results Summary

Strong and clear western blot signal at 1:1000 dilution using mouse lung tissue. Chemiluminescent detection showed low background and good reproducibility. Both H3K27M mutant and total Histone H3 signals were detected. Overall, the antibody performed reliably for western blot analysis.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Strong signal.

The Bad

None.

The Bottom Line

I was happy with the results.

Share your experience with other scientists. Write a Review! »

Join the discussion