Versatile and Reliable Desalting Solution for High-Throughput Workflows

MD Anderson Cancer Center - University of Texas
Cancer System Imaging (Diagnostic Imaging Division)
Lab Technician

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Company:

Thermo Fisher Scientific

Product Name:

Zeba™ Spin Desalting Columns 7K MWCO, 0.5–100 mL

Catalog Number:

89882

Zeba Spin Desalting Columns (7K MWCO) deliver fast, consistent protein recovery and sample cleanup across multiple formats, making them a practical choice for busy labs running mass spectrometry, HPLC, or assay development.

Experimental Design and Results Summary

Application

Sample desalting and protein recovery for mass spectrometry, HPLC, capillary electrophoresis, metabolite screening, and assay development.

Starting Material

Protein samples requiring buffer exchange or desalting. Compatible with 0.5–100 mL sample volumes across column, plate, and cartridge formats.

Tips

Equilibrate the resin thoroughly before loading your sample Avoid overloading — stay within the recommended volume range Spin speed and time matter — follow the protocol closely for best recovery Choose the right format (column vs plate) based on your throughput needs

Results Summary

Consistently high protein recovery with effective salt removal. Performance is reliable across formats with minimal sample loss and clean outputs ready for downstream analysis.

DOI or PMID #

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Summary

The Good

Ready-to-use, high-throughput compatible, and versatile across multiple applications and sample volumes.

The Bad

7K MWCO limits use with smaller molecules, and per-sample cost can be high for large-scale runs.

The Bottom Line

A dependable, lab-friendly desalting solution that saves time without compromising sample quality — worth it for labs prioritizing throughput and reproducibility.

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