Sharp, Low-Background Nuclear Stain Perfect for Multiplexing

Stanford University
Biochemistry
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Biotium

Product Name:

EverBrite™ Hardset Mounting Medium with NucSpot® 640

Catalog Number:

23016-T

I use Mounting Medium with NucSpot® 640 for nuclear staining in multiplex imaging, as DAPI-containing mounting media can interfere with other UV-excitable probes like BFP or Filipin.

Experimental Design and Results Summary

Application

Immunofluorescence

Starting Material

Fixed cells

Tips

Aliquot is small quantities for repetitive usage.

Results Summary

The image shows clear nuclear staining with NucSpot® 640. Other fluorescent signals, such as BFP or Filipin, are preserved, allowing effective multiplexed imaging.

DOI or PMID #

N/A

Image Gallery

Summary

The Good

Very specific, and low background.

The Bad

Not provided in a dropper bottle, which would be easier to use.

The Bottom Line

It is a great dye, and superior labeling of nucleus (often better than DAPI).

Join the discussion