Highly Efficient Kit from Sigma-Aldrich for Detecting Apoptosis in Primary Cells.

University of Tennessee HSC
Physiology
Postdoctoral Researcher

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Company:

Sigma-Aldrich

Product Name:

Annexin V-FITC Apoptosis Detection Kit

Catalog Number:

APOAF

The study aimed to investigate the role of MEK in cell survival. To achieve this, smooth muscle cells were treated with thrombin in the presence and absence of PD98059, a MEK inhibitor. The treated cells were subsequently examined for apoptosis using a kit from Sigma-Aldrich. The results indicated that apoptosis increased when MEK was inhibited.

Experimental Design and Results Summary

Application

In vitro assay

Starting Material

Primary cells

Tips

None

Results Summary

This kit effectively detected apoptosis in primary cells. The results indicated that MEK inhibition increased apoptosis.

DOI or PMID #

N/A

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Summary

The Good

Simple protocol and high efficacy.

The Bad

None.

The Bottom Line

One of the best kits to detect apoptosis in primary cells.

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