This Selective Potent Arp2/3 Inhibitor From Bio-Techne Works Well

University of Tennessee HSC
Physiology
Postdoctoral Researcher

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Company:

Bio-Techne

Product Name:

CK 666 (Arp2/3 selective inhibitor)

Catalog Number:

3950

This study aimed to test the effect of Arp2/3 inhibition on VEGFA-induced actin polymerization in endothelial cells. We observed that the Arp2/3 inhibitor, plate_number_1, blunted the VEGFA-induced actin polymerization, and its inhibition was potent.

Experimental Design and Results Summary

Application

Actin polymerization assay

Starting Material

Endothelial cells

Tips

None

Results Summary

CK666 was found as a potent inhibitor of Arp2/3 which blocked VEGFA-induced actin polymerization in endothelial cells.

DOI or PMID #

N/A

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Summary

The Good

A selective and potent inhibitor that works well.

The Bad

None

The Bottom Line

A great product of R&D systems.

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