A Specific Alpha SMA Antibody From Thermo Fisher Scientific

Neuroscience
Wisconsin University
Postdoctoral Researcher

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Company:

Thermo Fisher Scientific

Product Name:

Alpha-Smooth Muscle Actin Monoclonal Antibody

Catalog Number:

MA1-06110

Clone Number:

N/A

Our research focuses on understanding multiple pathological processes in ocular diseases. The specific goal of this experiment was to evaluate the effects of age on myofibroblast transformation. This antibody provided excellent staining for smooth muscle actin positive myofibroblasts.

Experimental Design and Results Summary

Applications

Immunofluorescence

Sample

Cultured mouse fibroblast

Primary Incubation

1:500 at 4 degrees celsius for overnight

Blocking Agent

5% normal donkey serum

Secondary Incubation

Alexa fluor anti-mouse IgG at 1:500 for 1 hr at room temp

Tertiary Incubation

N/A

Detection

Fluorescence

Results Summary

Immunofluorescence labeling with this antibody provided robust fluorescence signals specific to smooth muscle actin expressed in myofibroblasts (red).

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Robust signals.

The Bad

None.

The Bottom Line

This antibody is highly recommended for detecting fibroblast to myofibroblast transformation in vitro.

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