Superb Reagent to Re-stimulate Human T-Cells

University of Tennessee HSC
College of Medicine
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

Miltenyi Biotech

Product Name:

CytoStim™, human

Catalog Number:

130-092-172

I used cytoStim reagent as a positive control to restimulate CD4+ and CD8+ T-cells present in PBMCs. After stimulation for 4-8h PBMCs were stained with fluorochrome antibodies to check the increase in expression of surface markers.

Experimental Design and Results Summary

Application

Stimulation of human T-cells

Starting Material

PBMCs

Tips

If possible use freshly isolated PBMCs

Results Summary

5-10% increase in the expression of activation surface markers on T-cells were observed compared to non-stimulated PBMCs.

DOI or PMID #

N/A

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Summary

The Good

Easy protocol and non-toxic reagent.

The Bad

Bit expensive.

The Bottom Line

Works great as a positive control to standardize your protocol for test samples.

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