Excellent N-Cad Antibody for Western Blot From Abcam

Pathology
Sao Paulo State University
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

Abcam

Product Name:

Anti-N Cadherin antibody [5D5] - Intercellular Junction Marker

Catalog Number:

ab98952

Clone Number:

N/A

This antibody was used in a study that investigated the induction of EMT in amnion epithelial cells (AEC) in response to inflammation and infection associated with spontaneous preterm birth (SPTB). It was published in Reproduction in 2020 (Silva et al., Inflammation, but not infection, induces EMT in human amnion epithelial cells. Reproduction. 2020 Oct;160(4):627-638).

Experimental Design and Results Summary

Applications

Western blot

Sample

Human amnion epithelial cells

Primary Incubation

1 hour at 4°C in blocking reagent (1:600 dilution)

Blocking Agent

5% nonfat milk in 1× Tris-buffered saline-Tween 20 (TBS-T)

Secondary Incubation

1:10000, 2 hours, RT

Tertiary Incubation

N/A

Detection

FACSCalibur (Becton Dickinson), software CellQuest version 4

Results Summary

The results looks good using this dilution. The band is clear and the run does not have a lot of background.

DOI or PMID #

10.1530/REP-20-0283

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Good quality and low background.

The Bad

The dilution used was different from what the manufacturer suggested.

The Bottom Line

Good signal, appropriate results for this marker.

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