Marvelous CK5 Antibody From BioLegend

Surgery
University of Texas Southwestern Medical Center
Research Scientist

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Quality of Results

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Company:

BioLegend

Product Name:

Cytokeratin-5 Antibody

Catalog Number:

PRB-160P

Clone Number:

N/A

We used this to stain cytokeratin 5 on mouse mammary glands and it showed very clear and convincing membrane staining. For immunofluorescence (IF) staining, FFPE sections were deparaffinized, and rehydrated, and then antigen retrieval was done using citric acid buffer (pH 6.0). It was then treated with 0.3% H2O2 and 0.25% Triton X 100 solution. Then sections were incubated with this antibody at 1:1000 at 4 degrees O/N, washed 3X with PBS, then incubated with Alexa Fluor 488 goat anti-rabbit IgG (Life Technologies; A11008) secondary antibody, and slides were counterstained with DAPI (Sigma Aldrich). A representative picture was taken under a Leica IF Microscope for evaluation.

Experimental Design and Results Summary

Applications

Immunofluorescence

Sample

Mouse mammary gland

Primary Incubation

1:1000, 4 degree, O/N

Blocking Agent

2.5% horse serum

Secondary Incubation

1:1000, 1h at RT

Tertiary Incubation

None

Detection

IF microscope

Results Summary

Showed very clear staining of CK5 on mouse mammary epithelial tissue. We used this to stain cytokeratin 5 on mouse mammary glands and it showed very clear and convincing membrane staining. For immunofluorescence (IF) staining, FFPE sections were deparaffinized and rehydrated and then antigen retrieval was done using citric acid buffer (pH 6.0) and then treated with 0.3% H2O2 and 0.25% Triton X 100 solution. Then sections were incubated with this Antibody at 1:1000 at 4 degree O/N and washed 3X with PBS and then incubated with Alexa Fluor 488 goat anti-rabbit IgG (Life Technologies; A11008) secondary antibody, and slides were counterstained with DAPI (Sigma).

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Clear staining.

The Bad

N/A

The Bottom Line

Reliable CK5 antibody.

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