Great Heat Shock Protein 27 Antibody From MyBioSource.com

Physiology
University of Tennessee HSC
Postdoctoral Researcher

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Company:

MyBioSource.com

Product Name:

Heat Shock Protein 27 Antibody

Catalog Number:

MBS395181

Clone Number:

N/A

To test the time course effect of a particular growth factor on Heat Shock Protein 27 expression in mice, the primary cell lines were growth-arrested for 12 hrs. in a medium devoid of FBS. The synchronized cells treated without or with growth factor, prepared protein extracts, and an equal amount of proteins were resolved in 12%SDS-PAGE. The resolved proteins were then western transferred in a nitrocellulose membrane and probed with a specific antibody. The selection of Ab was based on the merits indicated in the antibody flyer.

Experimental Design and Results Summary

Applications

Western blot

Sample

Mouse primary cell whole cell lysate

Primary Incubation

Dilution (1:1000) in 5% BSA prepared in 1x TBST, overnight incubation at 4 degrees celsius.

Blocking Agent

skimmed milk (5%) prepared in 1x TBST.

Secondary Incubation

Goat anti-mouse IgG HRP, dilution (1:4000) in 5% skimmed milk prepared in 1x TBST, 2hr at RT.

Tertiary Incubation

None

Detection

Enhanced chemiluminescent detection in X-Ray films.

Results Summary

Heat Shock Protein 27 from MyBioSource.com has detected a very faint band of Heat Shock Protein 27 protein. Interestingly, a non-specific light-intensity band with high molecular weight was also detected.

DOI or PMID #

None

Additional Notes

None

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Summary

The Good

High specificity of Ab for Heat Shock Protein 27.

The Bad

Antibodies moderately cross-reacted with other nonspecific epitopes.

The Bottom Line

Excellent antibody for Heat Shock Protein 27 detection.

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