Antibody by Abcam With Good Staining But Some Background is Present

Wake Forest Baptist Health

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Abcam

Product Name:

Anti-PGP9.5 antibody [13C4 / I3C4]

Catalog Number:

ab8189

Clone Number:

N/A

This antibody was used to mark nervous tissue to assess the response of the rabbit anal sphincter to injury and treatment.

Experimental Design and Results Summary

Applications

Immunohistochemistry

Sample

FFPE Rabbit Anal Sphincter

Primary Incubation

1:1000

Blocking Agent

BLOXALL for 10min and Leica Superblock for 10min.

Secondary Incubation

1:250

Tertiary Incubation

N/A

Detection

ImmPACT DAB substrate

Results Summary

This antibody provided good staining of nerves in rabbit tissue that enabled quantification. Specific staining was nice and dark but background was present on all sections stained. Most significant background was in skeletal muscle.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Good staining with minimal antibody needed and standard staining conditions.

The Bad

Background staining in skeletal muscle was more than ideal.

The Bottom Line

It was good enough to detect nerves and quantify them in rabbit tissue.

Share your experience with other scientists. Write a Review! »

Join the discussion