Great Cholesterol Assay Kit From Abcam

University of Texas Southwestern Medical Center
Surgery
Research Scientist

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Company:

Abcam

Product Name:

Cholesterol Assay Kit - HDL and LDL/VLDL

Catalog Number:

ab65390

We previously pharmacologically identified a small metabolite that regulates energy expenditure in mice. In this study, we want to explore if genetic manipulation of this metabolite via gene knockout of the synthase in mice results in metabolic dysfunctions. An important characterization is circulating lipids, especially cholesterol levels. We, therefore, use this kit to measure HDL and LDL/VLDL levels in mouse serum. This kit gives nice standard curves and absolute quantifications of circulating cholesterol.

Experimental Design and Results Summary

Application

Cholesterol measurement

Starting Material

N/A

Tips

Keep in -20°C.

Results Summary

Using this kit, we found that genetic deficiency of a metabolite of interest results in decreased HDL to LDL/VLDL ratio, suggesting dysregulated lipid metabolism.

DOI or PMID #

N/A

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Summary

The Good

Consistent quality.

The Bad

A little expensive.

The Bottom Line

This kit gives nice standard curves and absolute quantifications of circulating cholesterol.

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