Great Type 4 Collagenase for Tissue Dissociation

Houston Methodist

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Company:

Worthington Biochemical Corporation

Product Name:

Collagenase, Type 4

Catalog Number:

LS004189

The goal of this research is to isolate single cells from tumor and stain them with antibodies and do flow cytometry to determine the cell percentage. We used this Type 4 Collagenase for the tissue dissociation to get single cells.

Experimental Design and Results Summary

Application

Tissue dissociation

Starting Material

Fresh tissue

Tips

The concentration is 1 mg/mL. Digestion time is about 1 hour.

Results Summary

We were able to harvest single cells after Type 4 collagenase digestion. The cell surface markers were not damaged, and the flow cytometry results looks good.

DOI or PMID #

None

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Summary

The Good

Reliable

The Bad

Expensive

The Bottom Line

Expensive but great, highly recommended.

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