Good Kit for Protein Quantification

University of Illinois at Chicago
Anatomy and Cell Biology
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Thermo Fisher Scientific

Product Name:

Pierce BCA Protein Assay Kit

Catalog Number:

23227

BCA protein assay kit was used to determine protein concentration in lysates from primary brain endothelial cells before Western blot analysis for vesicle-associated proteins.

Experimental Design and Results Summary

Application

Protein quantification for Western blot.

Starting Material

BSA standard and primary cell lysate.

Tips

Working range for kit is 20-2,000 ug/mL

Results Summary

Standard curve from BSA standards was consistent and easy to read with standard plate reader. However, protein concentration in cell lysates was too low to be measured by BCA kit.

DOI or PMID #

N/A

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Summary

The Good

Easy to use.

The Bad

Working range is too high for small samples.

The Bottom Line

This kit is very easy to use and produces a good standard curve to measure protein concentrations against. However, the working range is too high for small cell lysate samples.

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