Great PCR Mix for Genotyping

University of Illinois at Chicago
Anatomy and Cell Biology
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

ABclonal

Product Name:

PowerPol 2X PCR Mix

Catalog Number:

RM20388

ABclonal PowerPol kit was used for fast genotyping of mice from cross between Cav-1 KO and Claudin-5 GFP mice.

Experimental Design and Results Summary

Application

PCR

Starting Material

Mouse ear or tail tissue

Tips

HotSHOT protocol used to prepare genomic DNA template (Truett, et al. 2000).

Results Summary

Genotyping PCR protocol with boiled, non-digested tissue worked very well. Both Cav-1 and GFP genotypes were clear with minimal non-specific product amplification.

DOI or PMID #

N/A

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Summary

The Good

Very inexpensive, contains loading dye.

The Bad

Not for use in cloning applications.

The Bottom Line

This PCR mix is the cheap and works very well for genotyping applications. Highly recommend.

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