Great CD68 Antibody For Flow Cytometry

Anatomy and Cell Biology
University of Illinois at Chicago
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

BioLegend

Product Name:

PE anti-mouse CD68 Antibody

Catalog Number:

137013

Clone Number:

FA-11

Info:Supplier Page View Product Specs

Browse Similar Products: CD68 Antibodies

Anergy/exhaustion of primary T cells was measured through flow cytometry by analyzing CD68 expression in response to IL-2 stimulation.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Primary mouse T cells

Primary Incubation

1:100, 1 hour on ice

Blocking Agent

TruStain FcX (anti-mouse CD16/32) Antibody

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Cytoflex S flow cytometer (Beckman Coulter)

Results Summary

CD68 is expressed in low levels in unstimulated T cells and increased upon activation. Using this antibody, we were able to identify what percentage of T cells from inflamed tissues failed to increase CD68 in response to in vitro activation with IL-2.

DOI or PMID #

N/A

Additional Notes

Cells permeabilized with FoxP3 Fix/Perm (BioLegend) prior to staining with CD68-PE antibody.

Image Gallery

Summary

The Good

Very bright staining. Clear positive and negative populations.

The Bad

None.

The Bottom Line

This antibody worked very well to analyze intracellular CD68 in T cells and we will continue to use it in our research.

Share your experience with other scientists. Write a Review! »

Join the discussion