Great Caveolin-1 Antibody for Flow Cytometry

Anatomy and Cell Biology
University of Illinois at Chicago
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technology

Product Name:

Caveolin-1 Rabbit mAb AF647

Catalog Number:

31411S

Clone Number:

D46G3

Changes in Caveolin-1 expression brain endothelial cells in response to respiratory infection was measured by flow cytometry.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Primary mouse brain endothelial cells

Primary Incubation

1:100, 30 minutes on ice

Blocking Agent

TruStain FcX PLUS (anti-mouse CD16/32) Antibody

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Cytoflex S Flow Cytometer (Beckman Coulter). APC channel

Results Summary

Caveolin-1 staining, as detected by flow cytometry, was bright and expression was elevated in the majority of mouse brain endothelial cells.

DOI or PMID #

N/A

Additional Notes

Cells permeabilized with FoxP3 Fix/Perm (Biolegend)

Image Gallery

Summary

The Good

Very bright staining.

The Bad

Expensive antibody.

The Bottom Line

This antibody works very well for flow cytometry staining. It is expensive, but we haven't found a less expensive option that works as well.

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