Strong Stain, Easy Optimization

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Invitrogen

Product Name:

SYTOX™ Green Nucleic Acid Stain - 5 mM Solution in DMSO

Catalog Number:

S7020

Used to study the release of NETs from neutrophils in response to S. aureus stimulation in vitro. Great signal, enabling the identification of extracellular DNA / NETs released from neutrophils.

Experimental Design and Results Summary

Application

IF

Starting Material

Mouse neutrophils

Tips

Final concentration 0.1 µM

Results Summary

In the figure below, purified mouse neutrophils were adhered to plates and then stimulated with buffer alone, or buffer containing S. aureus. After 90 minutes, sytox green was added to cells and then imaged after 15 minutes of dye addition on live cells. The green puffs (white arrow) are indicative of cells undergoing NETosis.

DOI or PMID #

N/A

Related Categories

Image Gallery

Summary

The Good

Good signal to noise!

The Bad

NA

The Bottom Line

Cell impermable, so great for the study of extracellular DNA.

Join the discussion