Very Effective PerCP/Cy5.5 Anti-CD45.2

Microbiology and Immunology
UCSF
Research Scientist

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

BioLegend

Product Name:

PerCP/Cyanine5.5 anti-mouse CD45.2 Antibody

Catalog Number:

109828

Clone Number:

104

Info:Supplier Page View Product Specs

Browse Similar Products: CD45.2 Antibodies

After doing an adoptive transfer of 1:1 ratio of CD45.1+ and CD45.2+ Natural Killer cells into a double positive B6 mouse, we used the PerCP/Cyanine5.5 anti-mouse CD45.2 Antibody to do a FACS analysis of the blood of the recipient mouse. We did this to ensure a successful transfer of a 1:1 ratio of the donor cells.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse blood lymphocytes

Primary Incubation

incubated 30min at 4°C in blocking reagent (1:100 dilution)

Blocking Agent

2.5% heat-inactivated Fetal bovine serum; 1mM EDTA, azide in PBS

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

FACS LSRII (Becton Dickinson), DiVa analysis software

Results Summary

When used in par with an anti-CD45.1 antibody, the PerCP/Cyanine5.5 anti-mouse CD45.2 antibody helped us identify a successful 1:1 injection of CD45.1 and CD45.2 NK cells into our donor mice.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

The results were specific and we could use the antibody with other fluorophores.

The Bad

We had to use a significant amount of antibody.

The Bottom Line

Antibody has great signal. Highly recommended.

Share your experience with other scientists. Write a Review! »

Join the discussion