Extremely Reliable and Clean LTB4-R1 Antibody

Overall

Quality of Results

Ease-of-Optimization

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Company:

Merck

Product Name:

Anti-LTB4-R1

Catalog Number:

MABF2769

Clone Number:

7A8

Info:Supplier Page 

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Used to study GPCR trafficking in mouse neutrophils. Reduction in signal is consistently seen in response to cells exposure of LTB4R1 classical ligand, LTB4, indicative of agonist induced internalisation.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse Neutrophils

Primary Incubation

1:100

Blocking Agent

FC block

Secondary Incubation

Anti-mouse PE

Tertiary Incubation

na

Detection

YETI flow cytometer

Results Summary

In figure 1, we see upregulation of LTB4R1 to the plasma membrane of neutrophils in response to GM-CSF and TNFa priming.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Great product, very specific.

The Bad

No off the shelf PE-conjugated version.

The Bottom Line

This antibody has been instrumental in our labs study of GPCR trafficking in mouse neutrophils.

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