Reliable Reagent with a Linear Response

MD Anderson Cancer Center - University of Texas
Cancer System Imaging (Diagnostic Imaging Division)
Lab Technician

Overall

Quality of Results

Ease-of-Optimization

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Company:

Invitrogen

Product Name:

alamarBlue™ Cell Viability Reagent

Catalog Number:

DAL1025

I use alamarBlue as redox indicator to evaluate metabolic function and cellular health. Ready to use: just add the solution to the cells (in complete media without washing or cells lysis), incubate for at least 3 hours at 37°C and then read the absorbance to detect cytotoxicity. The results are always reliable as the reagent is very sensitive detecting few cells/ well.

Experimental Design and Results Summary

Application

Cytotoxicity

Starting Material

Cells in complete media

Tips

If I need higher sensitivity I used to increase the incubation time up to 4 hours.

Results Summary

I use alamarBlue as redox indicator to evaluate metabolic function and cellular health. Ready to use: just add the solution to the cells (in complete media without washing or cells lysis), incubate for at least 3 hours at 37°C and then read the absorbance to detect cytotoxicity.

DOI or PMID #

N/A

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Summary

The Good

Ready to use, reliable results, high sensitivity.

The Bad

Different checks before understanding the best incubation time.

The Bottom Line

The results are always reliable as the reagent is very sensitive detecting few cells well.

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