Great CD11b Antibody for Flow

BMS
UCSF
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Biolegend

Product Name:

Anti-mouse CD11b BV510

Catalog Number:

101263

Clone Number:

M1/70

Info:Supplier Page View Product Specs

Browse Similar Products: CD11b Antibodies

The nutritional composition of diet fundamentally modulates core physiological systems, including whole-body metabolic programs and the immune system– the mammalian defense to homeostatic alteration. Ketogenic diets (KDs) are extremely high in fat and very low in carbohydrates and have been shown to dramatically rewire whole-body metabolism. The KD-induced metabolic adaptation improves many physiological processes including aging, fatty acid utilization, and glucose homeostasis. However, the effects of KDs on host immunity remain less explored1–3. Thus, the overall objective of my PhD studies will be to elucidate how KDs affect the immune response in adaptive and maladaptive contexts.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

mouse skin sample

Primary Incubation

1:100

Blocking Agent

N/A

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometry

Results Summary

Great signal to detect CD45+ CD11b+ myeloid population from mouse skin samples. I tried both 1:100 and 1:200 dilutions and both worked fine.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Good signal.

The Bad

N/A

The Bottom Line

High recommended if that fits your panel.

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