Great Caspase-3 Antibody

August 31, 2022

Department of Internal Medicine
East Tennessee State University
Graduate Student

Overall

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Company:

Santa Cruz Biotechnology

Product Name:

caspase-3 Antibody (E-8) FITC

Catalog Number:

sc-7272 FITC

Clone Number:

N/A

An increased caspase 3 level was observed in HIV-infected cells suggesting a possible DNA damage and repair pathway initiation after an HIV infection in CD4 T cells.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human T cells

Primary Incubation

1:50

Blocking Agent

Permialization buffer

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometry

Results Summary

We observed increased caspase-3 expression in HIV-infected CD4 T cells. An increased caspase expression which is a lysosomal enzyme involved in triggering apoptosis elucidates the adverse effects of HIV infection in T cells.

DOI or PMID #

https://doi.org/10.3389/fimmu.2020.626431

Additional Notes

N/A

Image Gallery

Summary

The Good

Good antibody.

The Bad

N/A

The Bottom Line

Highly recommend, great antibody.

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