Titration Required but Yields Pure Samples

Columbia University Medical Center
Microbiology and Immunology
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

StemCell Technologies

Product Name:

EasySep™ Human CD3 Positive Selection Kit II

Catalog Number:

17851

We isolate T cells from human tissues and extract the DNA for carbon dating analysis. These kits allow us to isolate T cells without the use of FACS.

Experimental Design and Results Summary

Application

Retrospective Carbon Birth Dating

Starting Material

N/A

Tips

Titration is necessary.

Results Summary

The first time using this kit did not produce great results, but once I did a titration experiment, I achieved samples of at least 95% purity. For many of my samples, I only need at most 50% of the recommended cocktail amount.

DOI or PMID #

N/A

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Summary

The Good

High sample purity.

The Bad

Many time consuming wash steps.

The Bottom Line

While labor and time intensive, this kit is able to yield highly pure samples without the need for FACS.

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