Excellent Ras G12V Antibody

School of Natural Science
NUIG
Research Scientist

Overall

Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technology

Product Name:

Ras (G12V Mutant Specific) (D2H12) Rabbit mAb

Catalog Number:

14412

Clone Number:

N/A

Info:Supplier Page View Product Specs

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This antibody is specific for the detection of mutant RAS in the codon G12V. It cannot be used for other RAS mutant.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Mammary epithelial cell line, MCF10A

Primary Incubation

1:1000. Overnight. Cold room.

Blocking Agent

5% Milk in PBS

Secondary Incubation

1:7000. 1 hour at room temperature.

Tertiary Incubation

N/A

Detection

Bioluminescence (HRP-conjugated)

Results Summary

Mutant RASg12v was overexpressed through an inducibile doxycycline-dependent system. The ovexpression was strongly detected by this antibody after 24h of induction.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

It gives a sharp and specific band.

The Bad

Quite costly although very good antibody.

The Bottom Line

Very recommended antibody!

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