Anti-Human IgG for PBMC Staining

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Quality of Results

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Company:

BD Biosciences

Product Name:

PE-Cy™7 Mouse Anti-Human IgG

Catalog Number:

561298

Clone Number:

G18-145

Info:Supplier Page View Product Specs

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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining IgG in B cells (CD19+CD20+) in isolated PBMCs from a healthy donor (HD).

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Isolated PBMCs from HD peripheral blood

Primary Incubation

surface staining with IgG PE-Cy7 (0.1uL/50uL), 20 min at 4C

Blocking Agent

none

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

flow cytometer

Results Summary

We could stain IgG in B cells (CD19+CD20+) in isolated PBMCs from a healthy donor (HD).

DOI or PMID #

Additional Notes

Related Categories

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Summary

The Good

Works well

The Bad

N/A

The Bottom Line

It is a good option to stain human IgG.

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