Great for Innate Immune System Activation

EydisBio Inc.
R&D
Principal Investigator

Overall

Quality of Results

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Company:

Sigma Aldrich

Product Name:

LPS

Catalog Number:

L2630-10MG

Info: Supplier Page 

This LPS is a great reagent for use in animals to study the activation of immune cells in response to LPS challenge. It stored well and showed appropriate animal response.

Experimental Design and Results Summary

Application

Immune Challenge

Starting Material

N/A

Tips

Be careful with dosing as LD50 is low due to potency.

Results Summary

This reagent provides a robust immune cell activation indicated by TNF upregulation in animals following dosing.

DOI or PMID #

N/A

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Summary

The Good

Potent and increases inflammation

The Bad

Low LD50

The Bottom Line

This is a great reagent to treat animals to study inflammatory pathways.

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