Reliable Anti-CD44 BV510

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

Biolegend

Product Name:

Brilliant Violet 510™ anti-mouse/human CD44 Antibody

Catalog Number:

103043

Clone Number:

IM7

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at titrating anti-CD44 BV510.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse WT spleen

Primary Incubation

Surface staining with CD44 BV510 (1/200), 20 min at 4C

Blocking Agent

Fc block (2.4G2 clone)

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer

Results Summary

CD44 is expressed by all lymphocytes. We could titrate the antibody, and decided to use it at 1/200.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Reliable and good signal

The Bad

Nothing bad about it

The Bottom Line

Great, would buy again

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