Bright Anti-human CD127 PE

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

BD

Product Name:

PE Mouse Anti-Human CD127

Catalog Number:

557938

Clone Number:

HIL-7R-M21

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining CD127 in isolated PBMCs from peripheral blood of a healthy donor (HD).

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Isolated PBMCs from HD peripheral blood

Primary Incubation

surface staining with CD127 PE (1/10), 20 min at 4C

Blocking Agent

Fc block

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometry

Results Summary

We could stain CD127 that is expressed in T cells in the periphery.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Very bright

The Bad

NA

The Bottom Line

Good option

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