Mettl23 Detection in Cell Lines

Allied Research Unit, Biomedical Building, Faculty of Medicine and Surgery, University of Malta, Rm
University of Malta
Principal Investigator

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Company:

BosterBio

Product Name:

Mettl23

Catalog Number:

Custom

Clone Number:

N/A

This antibody was used to determine the level of protein expression in various cell lines in order to set up two groups (high vs low expression). This antibody was custom made because numerous suppliers have either stopped their production for this antibody or quality/specificity was low.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Human cell lines

Primary Incubation

1:500 with 1% BSA in TBS, incubated overnight, at 4oC, with shaking

Blocking Agent

5% BSA in TBS

Secondary Incubation

Licor IRDye 800 Goat anti Rabbit diluted 1:10000 with 1% BSA in TBS, incubated for 1 hour at RT , with shaking

Tertiary Incubation

None

Detection

Licor Odyssey IR Scanner

Results Summary

The antibody gave a detectable band at the expected size for all cell lines tested with no non-specific bands.

DOI or PMID #

N/A

Additional Notes

The antibody has very good stability at room temperature (transit took over 2 weeks and the ice packs had long melted before delivery)

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Summary

The Good

It gives consistent specific results

The Bad

The bands in most cases are weak

The Bottom Line

An important addition to our analysis repertoire. We will definitely buy it again

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