Calcium Channel Inhibitor Works Great

March 04, 2021

University of Texas medical branch
OBGYN
Group/Project Leader

Overall

Quality of Results

Ease-of-Optimization

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Company:

Tocris

Product Name:

SKF965365

Catalog Number:

1147/90

We have used SKF to study the role of the MRGPRX2 receptor in calcium mobilization via STIM1. A dose of 10-50uM SKF has effectively inhibited the calcium mobilization by various ligands.

Experimental Design and Results Summary

Application

Studying calcium mobilization

Starting Material

N/A

Tips

Easily soluble in PBS or water

Results Summary

10-50uM of SKF96365 HCL has inhibited the calcium mobilization and production of cytokines from human mast cells.

DOI or PMID #

32038646

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Summary

The Good

Solubility

The Bad

Nothing

The Bottom Line

Best product for studying calcium mobilization

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