Great Streptavidin-APC

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

ThermoFisher

Product Name:

Streptavidin, Alexa Fluor 647 conjugate

Catalog Number:

S21374

Clone Number:

S21374

Info: Supplier Page 

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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining B cells (CD19+).

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse WT Spleen

Primary Incubation

CD19 biot., 20min, 4°C

Blocking Agent

Fc block (2.4G2 clone)

Secondary Incubation

SA-APC 1/3200, 4°C, 15 min

Tertiary Incubation

N/A

Detection

Flow cytometer

Results Summary

We could stain B cells (CD19+). This SA works really well, it can be used at 1/3200. Thus, it is really unexpensive.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Very good signal

The Bad

N/A

The Bottom Line

I highly recomend to have this SA-APC, is it good and inexpensive.

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