Good Anti-Mouse IgM

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

Miltenyi Biotec

Product Name:

IgM Antibody, anti-mouse, REAfinity

Catalog Number:

130-116-215

Clone Number:

REA979

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining IgM on the surface of B cells.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse WT spleen

Primary Incubation

Surface staining with anti-IgM (1/25), 20 min at 4C

Blocking Agent

Fc block (2.4G2 clone)

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer

Results Summary

We could stain IgM very well.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Reliable and good signal

The Bad

N/A

The Bottom Line

I would buy it again.

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