Excellent Option to Detect CD44 in Mice

Charite Strasse 1
Deutsches Rheuma-Forschungszentrum
Research Scientist

Overall

Quality of Results

Ease-of-Optimization

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Company:

Biolegend

Product Name:

Brilliant Violet 510™ anti-mouse/human CD44 Antibody

Catalog Number:

103043

Clone Number:

IM7

B lineage cells play a major role in pathogenesis of autoimmune diseases through presentation of antigen to T cells, production of autoantibodies and inflammatory cytokines that modulate immune responses. We are interested in elucidating the biology of B lineage cells during autoimmunity. In this experiment, I wanted to titrate anti-CD44.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

wild-type mouse spleen

Primary Incubation

surface staining with, CD44 BV510 (1/100), CD19, etc (20 min, 4° in the dark)

Blocking Agent

clone 2.4G2 (Fc block)

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometry, violet laser

Results Summary

I could stain CD44+ cells in the spleen using this antibody at 1/100.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

The antibody works well.

The Bad

None

The Bottom Line

It can be used

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