Nice Antibody for Western Blot

Medicine
Harvard Medical School
Post-doctoral fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technologies

Product Name:

Anti-rabbit IgG, HRP-linked Antibody

Catalog Number:

7074S

Clone Number:

N/A

I used this as the secondary antibody to probe primary antibody (with rabbit as host) in Western blotting. Here, I determined the levels of endogenous Beta actin in THP1 cells treated with different compounds.

Experimental Design and Results Summary

Applications

Western Blot

Sample

THP-1 cells treated with different compounds

Primary Incubation

1:10000 dilution, 18 hours at 4 degrees with gentle shaking

Blocking Agent

5% non-fat dry milk in Tris buffer containing 0.1% Tween-20

Secondary Incubation

HRP-conjugated anti-rabbit antibody 1:20000 dilution, 1 hour at room temperature with gentle shaking

Tertiary Incubation

Not applicable

Detection

ECL based detection

Results Summary

Beta actin could be detected in all samples.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Specificity

The Bad

Nothing

The Bottom Line

This secondary antibody works like a charm for all primary antibodies (raised in rabbit) particularly from Cell signaling Technologies.

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