Nice Caspase 3 Antibody

Medicine
Harvard Medical School
Post-doctoral fellow

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

Cell Signaling Technologies

Product Name:

Caspase-3 antibody

Catalog Number:

14220S

Clone Number:

N/A

I used this antibody to probe for total caspase 3 (pro-apoptotic protein) in THP1 cells treated with different compounds.

Experimental Design and Results Summary

Applications

Western Blot

Sample

THP-1 cells treated with different compounds

Primary Incubation

1:1000 dilution, 18 hours at 4 degrees with gentle shaking

Blocking Agent

5% non-fat dry milk in Tris buffer containing 0.1% Tween-20

Secondary Incubation

HRP-conjugated anti-rabbit antibody 1:2000 dilution, 1 hour at room temperature with gentle shaking

Tertiary Incubation

Not applicable

Detection

ECL based detection

Results Summary

Treatment with different compounds yielded altered levels of Caspase 3 protein.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

It works well using manufacturer's recommended dilution

The Bad

It gives some background on the blot.

The Bottom Line

Overall, this antibody serves the purpose of detecting total Caspase 3 protein in Western blotting.

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