Usable Anti-Human CD20 Antibody

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

Miltenyi Biotec

Product Name:

CD20 Antibody, anti-human, VioGreen

Catalog Number:

130-113-379

Clone Number:

LT20

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody-secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining B cells (CD19+CD20+) in whole blood of a healthy donor (HD).

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human whole blood (Healthy Donor)

Primary Incubation

Anti-human CD20 VioGreen (1/200), 30', 4C

Blocking Agent

10µL Fc Blocking Reagent, 10min 4C

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer. VioGreen can be read in the BV510 channel.

Results Summary

As it is possible to observe in the figure, we could stain CD20+CD19+ B cells.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

It works

The Bad

It is not very bright

The Bottom Line

It works!

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