Reasonable Anti-STAT3 for Flow

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

Thermo Fisher Scientific

Product Name:

STAT3 Monoclonal Antibody (232209), FITC

Catalog Number:

MA5-23635

Clone Number:

232209

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at test staining STAT3.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Isolated PBMCs from HD peripheral blood

Primary Incubation

BD Phosflow Lyse/Fix Buffer + PermIII. anti-STAT3 FITC 1/5, 1h RT

Blocking Agent

5 µl FcR-Blocking

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer

Results Summary

There is positive staining in comparison with the isotype control.

DOI or PMID #

PMID: 32357246

Additional Notes

N/A

Related Categories

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Summary

The Good

It works

The Bad

It is not the brightest

The Bottom Line

Can be used

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