PVDF Membrane for Small Molecular Weight Protein Detection

Havard Medical School
Dpt of Cell Bio
Postdoctoral Researcher

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Company:

EMD MILLIPORE

Product Name:

Immobilon-PSQ Membrane, PVDF, 0.2 µm

Catalog Number:

ISEQ00010

I purchased this to probe small proteins (< 20 kDa) using immunoblotting. However, personally, I could not see the improvement when compared with 0.45 micron membrane side by side.

Experimental Design and Results Summary

Application

Immunoblotting

Starting Material

N/A

Tips

This membrane is thicker than 0.45 micron membrane. Wet them with MeOH before use.

Results Summary

Although I purchased this to probe small molecular weight proteins, now I use 0.45 micron membrane instead of this, as there was no advantage in using this 0.2 micron membrane.

DOI or PMID #

N/A

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Summary

The Good

Not sure

The Bad

No dramatic improvement in probing small proteins.

The Bottom Line

I would try this with a small samples, and if the trial works, then I'd order a whole box of the membrane.

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