Okay TCRgd Marker

M&I
COLUMBIA UNIVERSITY
Lab Director / Manager

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

BD Bioscience

Product Name:

BV421 Mouse Anti-Human TCR γδ

Catalog Number:

562560

Clone Number:

B1

Browse Similar Products: TCRgd Flow Cytometry Antibodies

Our lab studies lymphocytes isolated from various human organ pieces in order to study their localization throughout the body. One type of lymphocyte is the gamma-delta T cell and we wanted a marker for these cells. This marker is bright, but since the expression is low, the antibody staining is only okay.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human spleen cells

Primary Incubation

Cells were stained in 100ul FACS buffer with antibody at 1:50; for 1 hour on ice and in the dark. Cells were washed with FACS buffer and run in 100uL FACS buffer.

Blocking Agent

FACS

Secondary Incubation

None

Tertiary Incubation

None

Detection

BD Influx

Results Summary

This antibody works, but there is only a slight increase in expression so the staining separation isn't very high.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Easy to use

The Bad

Not a strong signal

The Bottom Line

This antibody is okay, but not robust for staining these cells.

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