eBioscience Fixation Solution to Fix Cells for Flow Cytometry

Johns Hopkins School of Medicine
Pharmacology and Oncology
Graduate Student

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Company:

Invitrogen

Product Name:

eBioscience™ Foxp3 / Transcription Factor Fixation/Permeabilization Concentrate and Diluent

Catalog Number:

00-5521-00

This eBioscience fixation kit came as 100mL fixation/perm diluent and 30mL fixation/permeabilization concentrate. Dilute the concentrate 1:3 with the diluent buffer. We use this solution to fix cells before the intracellular staining such as transcription factors for flow cytometry.

Experimental Design and Results Summary

Application

Fix cells for intracellular transcription factor staining

Starting Material

T cells

Tips

1:3 dilution of the concentrate

Results Summary

Ideal for fixing cells for following intracellular transcription factor staining.

DOI or PMID #

N/A

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Summary

The Good

Can leave cells in fixation overnight at 4 degree

The Bad

Leave cells in fixation too long might lead to overfix

The Bottom Line

This fixation is commonly used to fix cells before intracellular transcription factor staining.

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