Western Blot of Stem Cell Lysates Using CST Ras Antibody

Centre for Cellular and Molecular Medicine
Ludwig Cancer Research
Postdoctoral Researcher

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Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technology

Product Name:

Ras Antibody

Catalog Number:

3965

Browse Similar Products: Ras Western Blot Antibodies

Our aim is to examine the expression levels of Ras protein in glioma stem cells treated with an inhibitor against protein X. Stem cells were treated with inhibitor for 24 hours and the cell lysated were prepared by RIPA buffer lysis. Ran the lysates on 12% SDS-PAGE and western blot was performed.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Glioma stem cell lysate

Primary Incubation

1:10000, overnight at 4'C

Blocking Agent

5% BSA

Secondary Incubation

1:10000, anti-rabbit HRP conjugated antibody, 1hr at room temperature

Tertiary Incubation

N/A

Detection

West pico ECL reagent, Chemi doc

Results Summary

Observed a single band at 21KD corresponding to Ras protein in Stem cell lysates.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Excellent antibody and easy to optimize for performing western blots

The Bad

N/A

The Bottom Line

An excellent antibody which gives a single specific band at 21KD and easy to optimize. Dilution can be increased.

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