Very Sensitive Mouse LC3B Specific Antibody from MBL International

Cell Biology
Harvard Medical School
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

MBL international

Product Name:

LC3B

Catalog Number:

M186-3

Clone Number:

80000000000

I work on selective forms of autophagy, especially focusing on ribophagy and ER-phagy. I have used large numbers of antibodies for proteins related to autophagy. This LC3B antibody was very sensitive and specific. LC3A was not probed by this one.

Experimental Design and Results Summary

Applications

Western Blot

Sample

293T cells, over 30ug loading per well

Primary Incubation

1:1000 dilution in 5% BSA, TBST. overnight

Blocking Agent

5% non-fat milk in TBST

Secondary Incubation

1:20000 of IRdye700 (mouse)

Tertiary Incubation

TBST, 5min, 3 times

Detection

Odyssey Clx

Results Summary

This antibody worked better than the CST one that I used first. Some cells have lower abundance of LC3B. This antibody works for those cells.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Sensitivity and specificity over LC3A

The Bad

N/A

The Bottom Line

This antibody works well for cells with low LC3B expression level.

Share your experience with other scientists. Write a Review! »

Join the discussion