Very Good Anti-Mouse CD5 from BD Biosciences

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

BD Biosciences

Product Name:

CD5 Rat anti-Mouse, Brilliant Violet 786

Catalog Number:

740842

Clone Number:

53-7.3

Browse Similar Products: CD5 Flow Cytometry Antibodies

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody-secreting cells (ASC) and B cells in health and disease. In this experiment, we aimed at quantifying B-1a B cells (CD5+) in the peritoneal cavity of B6 mice.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Peritoneal Cavity lavage from WT B6 mice

Primary Incubation

surface staining with CD5 BV786, 20 min at 4C, 1:100

Blocking Agent

Fc block (2.4G2 clone)

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer with a violet laser

Results Summary

We could detect B1a (CD5+) cells, as well as T cells that are CD5++

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Detects T and B cells

The Bad

N/A

The Bottom Line

Good option for CD5

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