Good Antibody for ß-actin from Sigma

Orthopedic surgery
Johns Hopkins University School of Medicine
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

Sigma-Aldrich

Product Name:

Mouse anti-β-actin

Catalog Number:

A1978

Clone Number:

AC-15

My research focuses on molecular mechanisms of axon growth and guidance during neural development and axon regeneration after injuries to the central nervous system or peripheral nerves. For this western blot experiment, I want to use the expression of β-actin as an internal reference.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Mouse dorsal root ganglion cell culture

Primary Incubation

1:5000, overnight at 4°C

Blocking Agent

TBST (0.1%) containing 5% blotting-grade blocker

Secondary Incubation

1:2000, 1 hr at room temperature

Tertiary Incubation

N/A

Detection

KwikQuantTM Imager

Results Summary

The band of β-actin (bottom) looks good, even the unspecific band does not cause trouble.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

The antibody is ok

The Bad

There is a nonspecific band

The Bottom Line

This β-actin antibody works well.

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