Go 6983 Blocks LPA-Mediated COX-2 Expression

Medical University of Graz
Division of Cardiology
Postdoctoral Researcher

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Company:

Tocris Bioscience

Product Name:

Go 6983

Catalog Number:

2285/1

Human osteosarcoma cells were incubated with 20 μM Go 6983 for 30 min prior to treatment with 10 μM LPA to estimate COX-2 expression using Western blot analysis. Go 6983 abolished LPA-induced COX-2 expression

Experimental Design and Results Summary

Application

Cell culture

Starting Material

Human osteosarcoma cells

Tips

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Results Summary

Human osteosarcoma cells were incubated with 20 μM Go 6983 for 30 min prior to treatment with 10 μM LPA to estimate COX-2 expression using Western blot analysis. Go 6983 abolished LPA-induced COX-2 expression

DOI or PMID #

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Summary

The Good

Works as expected

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The Bottom Line

Go 6983 abolished LPA-induced COX-2 expression

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