Good Phospho-Btk Antibody from CST

R & D
Aptose Biosciences
Senior Research Associate

Overall

Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technology

Product Name:

Phospho-Btk (Tyr223) (D9T6H) Rabbit mAb #87141

Catalog Number:

87141

In our lab, we aim to study a small molecule kinase inhibitor’s activities in various cell lines by investigating phosphor-proteins of interest expression levels. This antibody that we used is good and reliable and worked without much optimization. Showed consistent results.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Ramos cell lysates

Primary Incubation

1:1000, overnight, four degrees Celsius

Blocking Agent

Licor blocking solution

Secondary Incubation

1:5000, 2 hours, room temp

Tertiary Incubation

None

Detection

Fluorescence imaging

Results Summary

The Ramos cells were treated with IgM stimulation (10ug/mL) for 10 minutes, and p-BTK Y223 signal increased as expected. This is a good antibody to use in Western blot.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Easy to use, reliable results

The Bad

None

The Bottom Line

This is a good antibody to use in Western blot.

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